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  • in reply to: Should I Increase My Allopurinol Dosage? #14717
    goutbgone
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    Thanks for your thorough response. ?I really do appreciate it. ?It is extremely comforting to know that there are people who genuinely care about helping people who suffer from gout and providing them with objective advice.

    Yesterday, I met with my doctor, and I talked with him about the research that I had done and my desire for us to come up with a target uric acid number. ?He indicated that he thinks I am already at a healthy level, so I am “already below any target he would have advised”. ?He said that dropping from 8.6 on February 8 to 5.8 on March 6 is a significant and rapid drop for UA. He says that it is likely to go even lower than 5.8 at my current dosage (is that true, btw? ?Does UA continue to drop after 1 month at a particular dosage? How long does it continue to impact UA before the dosage “levels off”, so to speak?). ?He recommended that I continue with my current 300 mg/day Allopurinol dosage, then get another blood test in 4 months to monitor my UA (and kidney/liver function too).

    Also, my kidney/liver function have been checked with each blood test since I started Allopurinol as well. ?Everything is fine, and, in fact, there was a huge drop in my ALT level from a range of 22-26 over the past few years, down to 6 on March 8 (all are healthy).

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